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Cryptococcus neoformans 

Cryptococcus neoformans (teleomorph: Filobasidiella spp.) is typically recovered from environmental samples as a nondescript yeast. This yeast is endemic throughout the world with different strains predominating in different locales. This yeast thrives in high nitrogen content material and is often associated with bird droppings. Outbreaks are typically associated with some kind of roosting site disturbance.

Cryptococcosis (an infection with Cryptococcus neoformans) is a trademark secondary infection in AIDS patients and most other cases are in patients with some other predisposing condition (such as lupus erythematosus, lymphoma, or leukemia). The infection is started by the inhalation of airborne fungal material and with ensuing infection in the lungs. The disease usually spreads to the brain and meninges, often proving to be fatal.

The main problem with the detection of Cryptococcus neoformans is that it is a nondescript yeast upon primary isolation. While most common indoor fungi can be differentiated to a degree by physical characteristics, yeasts are typically lumped into a single group. The differentiation of C. neoformans from other yeasts is based on biochemistry rather than direct observation and as such requires viable cultures of the organism. The analysis for C. neoformans can be performed in the typical 6-10 day turn around for viable cultures, but the test requires special media that do not allow other fungi to be reliably recovered or identified. Acceptable matrices include both swabs and bulk material are acceptable, as well as Andersen-style plates. For Andersen sampling the IAQ investigator should use Birdseed Agar (BBL) for the isolation medium, as it provides the quickest and most selective recovery of possible C. neoformans.

EMSL Analytical Code: M028

Sample retention time - 1 week

Full list of services provided for Cryptococcus neoformans ( click for details )
Laboratories providing Cryptococcus neoformans ( click for details )
Ann Arbor, MI - NVLAP Lab Code 101048-4Atlanta, GA - NVLAP Lab Code 101048-1Baton Rouge, LA - NVLAP Lab Code 200375-0Beltsville, MD - NVLAP Lab Code 200293-0Boston, MA - NVLAP Lab Code 101147-0Buffalo, NY - NVLAP Lab Code 200056-0Calgary, Alberta - NVLAP Lab Code 500100-0Carle Place, NY - NVLAP Lab Code 101048-10Charlotte, NC - NVLAP Lab Code 200841-0Chicago, IL - NVLAP Lab Code 200399-0Corporate - Cinnaminson, NJ - NVLAP Lab Code 101048-0Dallas, TX - NVLAP Lab Code 600111-0Denver, CO - NVLAP Lab Code 200828-0EMSL Canada - Montreal -- Quebec - NVLAP Lab Code 201052-0EMSL Canada -- Toronto - NVLAP Lab Code 200877-0EMSL Canada Inc. -- Ottawa - NVLAP Lab Code 201040-0Fort Lauderdale - NVLAP Lab Code 500085-0Houston, TX - NVLAP Lab Code 102106-0Huntington Beach, CA - NVLAP Lab Code 101384-0Indianapolis, IN - NVLAP Lab Code 200188-0Inland Empire, CA - NVLAP Lab Code 600239-0Kernersville, NC - NVLAP Lab Code 102104-0Las Vegas, NV - NVLAP Lab Code 600140-0Miami, FL - NVLAP Lab Code 200204-0Minneapolis, MN - NVLAP Lab Code 200019-0New York, NY - NVLAP Lab Code 101048-9Orlando, FL - NVLAP Lab Code 101151-0Pasadena, CA - NVLAP Lab Code 200232-0Phoenix, AZ - NVLAP Lab Code 200811-0Piscataway, NJ - NVLAP Lab Code 101048-2Plymouth Meeting, PA - NVLAP Lab Code 200699-0Raleigh, NC - NVLAP Lab Code 200671-0Rochester, NY - NVLAP Lab Code 600183-0S. Portland, ME - NVLAP Lab Code 500094-0Salem, NH - NVLAP Lab Code 201051-0San Diego, CA - NVLAP Lab Code 200855-0San Leandro, CA - NVLAP Lab Code 101048-3Seattle, WA - NVLAP Lab Code 200613-0St. Louis, MO - NVLAP Lab Code 200742-0Tampa, FL - NVLAP Lab Code 600215-0Vancouver, BC - NVLAP Lab Code 201068-0Wallingford, CT - NVLAP Lab Code 200700-0West Palm Beach, FL - NVLAP Lab Code 600206-0Weymouth, MA - NVLAP Lab Code 600217-0
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